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Coronary Artery Disease and Polycystic Ovaries
Title:Association between polycystic ovaries and extent of coronary
artery disease in women having cardiac catheterization
Author:M.A. Birdsall et al.
Address:Auckland, New Zealand
Source:Annals of Internal Medicine 126: 32-35 (January) 1997
Summary:A referral base of 143 women who were 60 years of age or
under underwent coronary quantitative angiography to evaluation of coronary
heart disease. All women had a history of chest pain or valvular disease.
Pelvic ultrasonography was used to assess the ovaries. Women without ovaries
were excluded from the study. A blinded comparison was made in the diagnostic
imaging studies. The authors found polycystic ovaries in 42% of the women
undergoing angiography. It was noted that the women with polycystic ovaries
were associated with more extreme coronary artery disease than the women
with normal ovaries.
Comment:Polycystic ovaries are a common ultrasound finding. It is
still not known exactly how this relates to polycystic ovarian syndrome,
but there is an obvious association. Many more women have PCO appearing
ovaries than the full spectrum of the syndrome. Many of the women are perfectly
fertile and/or have little excess hair. The consequences of the ultrasound
findings are only beginning to be investigated. It is to be expected that
Women with polycystic ovaries are faced with a male-like predisposition
toward cardiovascular disease and its associated risks. Obviously an early
identification could lead to earlier intervention and perhaps reduce the
personal and health costs of this major health issue and cause of morbidity
and mortality.
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