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Title:Thermal balloon ablation versus endometrial resection for the
treatment of abnormal uterine bleeding
Author: A. Gervaise, et al.
Address: Bourg-La-Reine, France
Source:Human Reproduction 14: 2743-2747 (November) 1999
Summary: This study was conducted to compare the clinical efficiency and
safety of a thermal uterine balloon system with hysteroscopic endometrial
resection in the treatment of dysfunctional uterine bleeding in 147 women. From
Nov. 1994 - April 1998, 73 women were enrolled in a prospective study of a
thermal uterine balloon system. The control group was chosen from analysis of the
records of patients undergoing resection and treated during the same period by
endometrial ablation for abnormal uterine bleeding. Inclusion in the study
required that women be > 40 years of age, with the exception of 2 patients in
each group who had a serious medical contraindication for pregnancy in addition
to menorrhagia. The indication for treatment in both groups was excessive
menstrual blood loss. The premenopausal women had either unsuccessful medical
therapy with progestins or were unwilling or unable to continue with medical
treatment. The post-menopausal patients were not willing to discontinue HRT.
Researchers found the operative time to be reduced significantly with the uterine
balloon technique. There were no intra-operative complications in either group
and postoperative morbidities were not statistically different. Multivariate
analysis noted 2 prior factors associated with failures: retroverted uterus with
thermal balloon ablation and age less than 43 years with endometrial resection.
The
overall success rate was not significantly different among the two groups, making
uterine balloon ablation appear to be as effective as endometrial resection. The
former is much easier to perform, making the technique readily reproducible,
especially by those with limited expertise in hysteroscopic surgery, and thus
more widely applicable and safer.