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CARS Archives

No association of birth weight and age at menopause
Title:Birth weight and age at menopause in Australian female twin pairs: exploration of the fetal origin hypothesis
Author: S. Treloar, et al.
Address: Queensland, Australia
Source:Human Reproduction 15: 55-59 (January) 2000
Summary: Researchers studied 323 Australian female twin pairs where both co-twins had reached menopause naturally and reported on their weight at birth. Regression analysis showed no linear association between the 2 variables. In monozygotic pairs (n=168) this allowed for control of genetic effects as well as gestation duration. No significant differences dependent on birth weight relative to co-twin were found for age at natural menopause in either mono or dizygotic twin pairs, even in pairs whose birth weights differed markedly. There was some indication that twins with premature ovarian failure were heavier at birth than twins with normal or later menopausal age. Researchers concluded that the hypothesis that lower birth weight is associated with earlier menopause is not supported by their study.
Comment: one of those interesting facts

 

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