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Adherence to postmenopausal hormone therapy
Title:Adherence to postmenopausal hormone therapy during the year after the initial prescription: A population-based study
Author: D. Hill, et al.
Address: Seattle, Washington
Source:American Journal of Obstetrics and Gynecology 182:270-276 (February) 2000
Summary: Women enrolled in a prepaid health plan participated in a telephone interview 12 to 15 months after newly initiating use of hormone replacement therapy to determine adherence to hormone therapy. Women were questioned as to whether they were still taking the hormones as first prescribed and reasons for switching or discontinuation. The number continuing the originally prescribed hormone regimen at 1 year was higher among continuous combined therapy users (68.9%) than among sequential therapy users (54.4%). Women who initiated continuous combined therapy were less likely to have switched regimens (10%) than were sequential users (20.2%) but only somewhat less likely to have discontinued use (21.2% vs. 25.4%). As a whole, women prescribed continuous combined therapy were less likely than those prescribed sequential therapy to quit or switch during the first year. Researchers concluded that although adherence was higher among women prescribed continuous combined HRT than sequential therapy, the high level of nonadherence in both groups suggests room for improvement of menopausal therapies so that women find them acceptable for sustained use.