#1 Cost efficient IVF service and education in U.S. Outpatient based IVF. Complete facilities include ultrasound suite,endocrine and andrology labs, and all IVF facilities. Located at new outpatient therapy center offering the latest in laparoscopy and hysteroscopy. Accomodations for visitors are nearby, safe, and inexpensive.

Puberty-Some new thoughts
Title: Rapid maturation of the reproductive axis during perimenarche independent of body composition
Author: R. Legro, et al.
Address: Hershey, PA
Source: The Journal of Clinical Endocrinology & Metabolism 85:1021-1025 (March) 2000
Summary: Researchers sought to identify the natural history of menarche in a large, healthy cohort of young women studied at 6-month intervals over a 4-year period beginning at premenarche. Subjects were 112 premenarchal Caucasian females. Researchers quantified reproductive hormones in 24-hour urine collections as a measure of daily output and measured body composition biometrically and with the use of dual energy x-ray absorptiometry scans. Sex steroid and gonadotropin levels changed exponentially in the year approaching menarche. FSH levels peaked at menarche and then progressively declined thereafter. Estradiol output increased rapidly in the year approaching menarche and then plateaus thereafter. The frequency of menstrual bleeding increased rapidly and plateaued at 1 year postmenarche. At 1 year, 65% had established a pattern of 10 or more menstrual episodes/yr, and by 3 years postmenarche this figure exceeded 90%. Researchers concluded that menarche occurs as a result of rapid maturation of the reproductive axis, independent of changes in body fat, and heralds the reestablishment of a negative sex steroid feedback loop that parallels the adult threshold.