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CARS Archives

You will never get pregnant?
Title: Spontaneous conception after a successful attempt at in vitro fertilization/intracytoplasmic sperm injection
Author: B. Hennely, et al.
Address: Dublin, Ireland
Source: Fertility and Sterility 73:774-778 (April) 2000
Summary: This retrospective postal questionnaire was sent to 530 people to study the incidence of spontaneous pregnancy in women who were not actively undergoing therapy after a successful attempt at IVF/ICSI and to characterize its pattern of occurrence. The rate of spontaneous conception among the 513 respondents was 20.7%. Younger women (less than 34) had a higher rate of spontaneous conception, as did those with a shorter duration of infertility. Women with unexplained infertility and endometriosis also were more likely to conceive. Few of those who had undergone ICSI conceived, whereas 21.6% of those whose partners had had sperm quality sufficient for IVF later conceived spontaneously. These pregnancies may be related to the ovarian stimulation given in the past or to the physiologic effects of pregnancy on the pituitary and endocrine systems.
Comment: It is amazing how many stories I hear from those who have been told they would never be pregnant, only subsequently to have several children. I am not sure what the purpose of that comment ever is. The tincture of time is a powerful therapy. I would not exclude relief of stress as the authors put forth as a possibility, but I would favor a resetting of the endocrine axis and mostly just their number coming up. Look also at the remaining 80% or so that may never have been pregnant without a technology.

 

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