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MENOPAUSE EXCERPTS -- Undigested but not indigestible
Title: Three stages of the menopausal transition from the Seattle midlife women's health study: Toward a more precise definition
Author: E. Mitchell, et al.
Address: Seattle, Washington
Source: Menopause: The Journal of the North American Menopause Society 7:334-349 (Sept./Oct.) 2000
Summary: The purpose of the project was to describe the development of specific criteria that define stages within the menopausal transition and to apply these criteria to classify midlife women into a stage of transition. Questionnaires about menstrual cycle changes and menstrual calendars were mailed yearly to a total of 184 midlife women taking no hormones and for whom data were available about initial menstrual cycle changes were studied. Intra-individual analyses for type and chronology of menstrual cycle changes during midlife for change in flow amount or duration, cycle length change, cycle irregularity, or skipped periods were conducted. Changes in flow or cycle length most frequently preceded irregularity without skipped periods, which preceded skipped periods. Initial changes began in the early 30s and most frequently between ages 40 and 44. Only 14% of the participants had irregularity as the initial change. Three stages of the menopausal transition were identified: early (flow and /or cycle length changes), middle (irregularity without skipping), and late (skipped periods). Age did not differentiate the three stages. Researchers believe that studies about the entire transition need to include women younger than age 45.