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Paternal Age
Title: Increasing paternal age is associated with delayed conception in a large
population of fertile couples: Evidence of declining fecundity in older men
Author: W. C. Ford, et al.
Address: Bristol, UK
Source: Human Reproduction 15:1703-1708 (August) 2000
Summary: Because controversy continues to surround the issue of aging and
male fertility, researchers conducted this study to determine the effect of male
age on the length of time it takes to conceive. This study is based on
pregnancies that resulted in the birth of a baby. Both the male and female
partners completed questionnaires at 18 weeks gestation. The questions were
related to such topics as parity, paternity, cohabitation, oral contraception,
education, smoking and obesity. Out of 8515 planned pregnancies, 74% were
conceived in £6 months, 14% in the second 6 months and 12% after more than a
year. After adjustment for 9 different variables, including the age of the woman,
the likelihood of conception within 6 or 12 months was lower in older men.
Compared to men less than 25 years old, the adjusted odds ratios for conception £12 months
were 0.62 in men aged 30-34, 0.50 in men 35-39, and 0.51 in men >40 years of age.
Comment: Still not too bad for the old men.