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BMI and IVF success
Title: Clinical assisted reproduction: Does body mass index of infertile women have an impact on IVF procedure and outcome?
Author: C. Wittemer, et al.
Address: Schiltigheim, France
Source: Journal of Assisted Reproduction and Genetics 17:547-552 (November) 2000
Summary: The purpose of this retrospective study was to determine if the body mass index (BMI) of patients related to the different parameters of the in vitro fertilization (IVF) procedure and outcome. Study participants were. Epidemiological features, characteristics of ovarian stimulation, number and quality of retrieved oocytes and pregnancy outcome were recorded in 398 couples divided in 3 groups. Group 1 was a BMI <20 (underweight), BMI from 20 to <25 (normal) and BMI >25 kg/m2 (overweight). Of the women, 21.8% were underweight and 22.3% were overweight. There was a significant increase in the FSH/LH ratio according to BMI. Group 3 used more gonadotropin ampoules together with a decrease in the number of collected oocytes. No significant difference was found in clinical pregnancy rates among underweight, normal weight and overweight patients. Miscarriage rate was increased in obese women.
Comment: A complicated issue. Is it weight or is it underlying ovarian dysfunction? Is it weight or is it PCOS? It would be curious to know more about those with spontaneous pregnancy loss. Weight alone is an overly simplistic, possibly prejudicial approach to the differences noted.