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PCOS and PIH
Title: Polycystic ovary disease and the risk of pregnancy-induced hypertension
Author: S. Kashyap, et al.
Address: Ontario, Canada
Source: The Journal of Reproductive Medicine 45:991-994 (December) 2000
Summary: Pregnancy-induced hypertension (PIH), the second-most-common cause of maternal mortality worldwide, has an incidence of 5% in the general population. This retrospective, case control study of women who had singleton pregnancies with injectable human menopausal gonadotropin (HMG) therapy was conducted to compare the incidence of PIH in patients with and without polycystic ovary disease (PCOD). Researchers compared 22 PCOD patients to 27 infertility patients without PCOD who became pregnant after receiving HMG for superovulation. The definition used for PIH was late pregnancy blood pressure >140/90 mm Hg on two readings six hours apart and a return to normal blood pressure by four to six weeks after giving birth. Researchers found that women with PCOD had a much higher occurrence of PIH (7/22) as compared to those women who did not have PCOD (1/27). It was determined that women with PCOD are at a much greater risk of PIH after undergoing ovulation induction. Researchers recommend that pregnant women with PCOD should have increased antenatal surveillance.
Comment: Small study in a select group of patients that makes an important point.